Pubblicazioni scientifiche

1. An indirect method to measure trimerization constants using surface plasmon resonance. Mattu M., Bendts C, Barbato G. Analytical Biochemistry (2009) Oct. (1) 126-8.
2. Structural Basis for Resistance of the Genotype 2b Hepatitis C Virus NS5B Polymerase to Site A Non-Nucleoside Inhibitors. Rydberg E.H., Cellucci A., Bartholomew L., Mattu M., Barbato G., Ludmerer S.W., Graham D.J., Altamura S., Pavonessa G., De Francesco R., Migliaccio G., Carfì A. J Mol Biol. 2009 Jul. (5)1048-59.
3. Structural and Biochemical Characterization of the Wild Type PCSK9-EGF(AB) Complex and Natural Familial Hypercholesterolemia Mutants. Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfí A. J Biol Chem. 2009 Jan. (284)1313-23.
4. Development and optimization of a binding assay for the Histone deacetylase 4 catalytic domain using surface plasmon resonance. Mattu M, Di Giovine P, Steinkuhler C, De Francesco R, Altamura S., Carfì A, Barbato G. Analytical Biochemistry Jun.(377) 267-9.
5. Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex. Vannini A, Volpari C, Gallinari P, Jones P, Mattu M, Carfi A, De Francesco R, Steinkuhler C, Di Marco S. EMBO Rep. 2007 Aug 10 (9):879-84.
6. Effects of pH and Low Densisty Lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation. Fisher TS, Lo Surdo P, Pandit S, Mattu M, Santoro JC, Wisniewski D, Cummings RT, Calzetta A, Cubbon RM, Fischer PA, Tarachandani A, De Francesco R, Wright SD, Sparrow CP, Carfi A, Sitlani A. J Biol Chem. 282 (28) pp 20502-20512, July 13 2007.
7. Structural basis for HIV-1 neutralization by a gp41 fusion intermediate-directed antibody. Luftig MA, Mattu M, Di Giovine P, Geleziunas R, Hrin R, Barbato G, Bianchi E, Miller MD, Pessi A, Carfi A. Nature Struct Mol Biol. 2006 Aug;13(8):740-7.
8. A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope. Miller MD, Geleziunas R, Bianchi E, Lennard S, Hrin R, Zhang H, Lu M, An Z, Ingallinella P, Finotto M, Mattu M, Finnefrock AC, Bramhill D, Cook J, Eckert DM, Hampton R, Patel M, Jarantow S, Joyce J, Ciliberto G, Cortese R, Lu P, Strohl W, Schleif W, McElhaugh M, Lane S, Lloyd C, Lowe D, Osbourn J, Vaughan T, EminiE, BarbatoG, KimPS, HazudaDJ, ShiverJW, Pessi A. Proc Natl Acad Sci U S A. 2005 (41)14759-64.
9. Nitrosylation of rabbit ferrous heme-hemopexin. Fasano M., Bocedi A., Mattu M., Coletta M, Ascenzi P. J Biol Inorg Chem. 2004 Sep 18.
10. Cyanide Binding to Truncated Hemoglobins: A Crystallographic and Kinetic Study. Milani M., Ouellet Y., Ouellet H., Guertin, M., Boffi, A., Antonini, G., Bocedi, A., Mattu, M., Bolognesi, M., Ascenzi P. Biochemistry, 2004 (43) 5213-5221.
11. Determination of ferric heme-human serum albumin by (1)H NMR relaxometry. Fasano M., Baroni S., Aime S., Mattu M., Ascenzi P. J Inorg Biochem. 2003 (95) 64-67.
12. The heme-iron geometry of ferrous nitrosylated heme-serum lipoproteins, hemopexin, and albumin: a comparative EPR study. Fasano M, Mattu M., Coletta M., Ascenzi P. J. Inorg. Biochem. 2002 (91) 487-490.
13. Effect of ibuprofen and warfarin on the allosteric properties of heam-human serum albumin: an spectroscopy study. Baroni S., Mattu M., Vannini A., Ascenzi P., Fasano M. Eur J. Biochem. 2001 (268) 6214-6220.
14. Inhibition of Saccharomyces cervisae Phosphomannose Isomerase by the NO-donor S- nitroso-acetyl penicillamine. Salvati L., Mattu M., Tiberi F., Ponticelli F., Ascenzi P. J.Enz Inib. 2001 (16) 287-292.
15. Monomer-dimer equilibrium and oxygen binding properties of ferrous Vitreoscilla hemoglobin. Giangiacomo L., Mattu M., Arcovito A., Bellenchi G., Bolognesi M., Ascenzi P., Boffi A. Biochemistry, 2001 (40) 9311-9316.
16. Modulation of the catalytic activity of cruzipain, the major cysteine proteinase from Trypanosoma cruzi, by temperature and pH. Salvati L., Mattu M., Polticelli F., Tiberi F., Gadoni L., Venturini G., Bolognesi M., Ascenzi P. Eur J Biochem. 2001 (268) 3253-3258.
17. Effect of bezafibrate and clofibrate on the heme-iron geometry of ferrous nitrosylated human serum heme-albumi An EPR study. Mattu M., Vannini A., Coletta M., Fasano M Ascenzi P. J. Inorg. Biochem.,2001 (84) 293-296.
18. NO donors inhibit Leishmania infantum cysteine proteinase activity. Salvati L., Mattu M., Colasanti M., Scalone A., Gradoni L., Venturini G., Ascenzi P. Biochim. Biophys. Acta,. 2001 (1545) 357-366.